Acebrophyline 100mg and N-Acetylcysteine 600mg Tablets

Acebrophylline +Acetylcysteine is a combination drug used in the treatment of chronic obstructive pulmonary disease (COPD). The medicine alleviates many symptoms of chronic obstructive pulmonary disease like shortness of breath, coughing, or wheezing (whistling sound while breathing). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Acebrophylline +Acetylcysteine belongs to the class of drugs called ‘mucolytic agents’ (cough/sputum thinner). Acebrophylline belongs to the class of bronchodilators that works by relaxing muscles and widening the airways of the lungs. Acetylcysteine belongs to the class of mucolytic agents (cough/sputum thinner) that result in thinning and loosening of phlegm (mucus) in the lungs, windpipe, and nose. Acebrophylline +Acetyl Cysteine breakdown the fiber (mucopolysaccharide) that makes the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing.

Take Acebrophylline +Acetylcysteine as per the prescribed dosage and duration. Strictly follow the dosage to see the optimum result in less time. Store the tablets in a cool and dry place, away from direct sunlight. Inform your doctor beforehand if you are allergic to Acebrophylline +Acetylcysteine and discuss your medical history. Avoid taking the tablets if you are suffering from low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), a heart attack, or kidney or liver diseases.

 Contraindications of Acebrophylline +Acetylcysteine

Avoid taking Acebrophylline +Acetylcysteine tablets if you are currently suffering from any of the following mentioned diseases. The list of health conditions  is given below:

• Low blood pressure
• Irregular heartbeats
• Hemodynamic instability (unstable blood pressure)
• Had a heart attack
• Kidney or liver diseases
• Hyperthyroidism (overactive thyroid)
• Viral infections
• Heart failure
• Asthma
• High blood pressure
• Fits
• Gastric or duodenal ulcers
• Heart diseases

Side Effects of Acebrophylline +Acetylcysteine

The side effects induced by Acebrophylline +Acetylcysteine differ in each individual and depend upon their physique, lifestyle factors, and response to the medicine. The side effects induced are mild to moderate and resolve over time. If the side effects persist or get severe, immediately consult medical consultation. The list of side effects is given below:

• Vomiting
• Heartburn
• Rash
• Itching
• Drowsiness
• Breathing problems
• Nasal inflammation
• Increased white blood cell count
• Abdominal discomfort
• Abdominal distension
• Diarrhea, Constipation
• Loss of appetite
• Esophageal bleeding
• Red spots or bumps
• Nausea
• Dizziness

Use of Acebrophylline +Acetylcysteine

Chronic obstructive pulmonary disease (COPD)

Drug Interaction

When two or more drugs are taken together, their combination can result in negative health implications. The same is true for certain food items and beverages. The medicine can also interact with certain health conditions.

Interaction with Drugs:

• Water pills (furosemide)
• Medicines used to treat gout (allopurinol)
• Antacid (cimetidine)
• Antibiotics (ciprofloxacin, erythromycin, amoxicillin, doxycycline, tetracycline, gentamicin, amikacin, neomycin)
• Drugs used to lower high blood pressure (diltiazem, verapamil)
• Heart-related medicines (isoprenaline)
• Anthelmintic (thiabendazole), corticosteroids (prednisone)
• Oral contraceptives (ethinylestradiol)
• Medicines used to treat chest pain (glyceryl trinitrate)
• Cough suppressants (dextromethorphan, codeine)

Interaction with Disease:

• Low blood pressure
• Irregular heartbeats
• Hemodynamic instability (unstable blood pressure)
• Had a heart attack
• Kidney or liver diseases
• Hyperthyroidism (overactive thyroid), irregular heartbeats
• Viral infections
• Heart failure
• Asthma, high blood pressure
• Fits, gastric or duodenal ulcers
• Heart diseases
• Kidney or liver insufficiency

Precautions and Warnings

1. Acebrophylline +Acetylcysteine does not provide instant relief. Hence, it is recommended to use an inhaler for instant relief.
2. Do not abruptly stop using the tablets as it can worsen your situation or your condition may again.
3. Avoid taking the tablets if you are pregnant, trying to conceive, or lactating. It can harm the fetus and infant due to its high potency.
4. It is not recommended for children below the age of 14 years.
5. Keep it away from your pets and properly dispose of discarded and expired medicines.

Frequently Asked Questions (FAQs)

1. Can Acebrophylline +Acetylcysteine interfere with laboratory tests?

Yes, acebrophylline+ acetylcysteine contains Acetylcysteine which may interfere with laboratory tests like urine ketone tests and may cause false test results.

2. What are the instructions for storage and disposal of Acebrophylline +Acetylcysteine?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of unused medicine.

3. Is it safe to smoke while taking Acebrophylline +Acetylcysteine?

No, you are not recommended to smoke while taking Acebrophylline +Acetylcysteine as it may reduce the effectiveness of the medicine and also damage your lungs.