Description
Enfumox SM 500 is a powerful broad-spectrum antibiotic combination that contains Amoxycillin Trihydrate (250 mg) and Sulbactam Pivoxil (250 mg). This synergistic formulation is highly effective in the treatment of bacterial infections caused by both Gram-positive and Gram-negative organisms, including those resistant to conventional antibiotics.
Manufactured with precision and quality assurance, Enfumox SM 500 works by inhibiting bacterial cell wall synthesis and neutralizing β-lactamase enzymes, which are often responsible for antibiotic resistance. The result is faster infection control, reduced relapse rates, and improved patient recovery.
Mechanism of Action
Amoxycillin Trihydrate (250 mg):
A semisynthetic penicillin antibiotic, Amoxycillin acts by inhibiting the synthesis of bacterial cell walls. It binds to penicillin-binding proteins (PBPs), disrupting peptidoglycan cross-linking, which leads to bacterial cell lysis and death. It is effective against a wide range of aerobic and anaerobic bacteria.
Sulbactam Pivoxil (250 mg):
Sulbactam is a β-lactamase inhibitor that prevents bacterial enzymes from breaking down Amoxycillin. This enhances the antibiotic’s spectrum of activity and makes it effective against β-lactamase–producing resistant strains of bacteria.
The combination of these two components ensures enhanced efficacy, broadened antibacterial coverage, and resistance prevention, making Enfumox SM 500 a reliable choice for various infections.
Indications for Use
Enfumox SM 500 is indicated for the treatment of infections caused by susceptible microorganisms, including:
- Upper and lower respiratory tract infections (such as bronchitis, pneumonia, sinusitis)
- Ear, nose, and throat infections (such as otitis media, tonsillitis, pharyngitis)
- Urinary tract infections (UTIs)
- Skin and soft tissue infections
- Bone and joint infections
- Gastrointestinal infections, including typhoid and bacterial gastroenteritis
- Dental infections and postoperative wound infections
By combining bactericidal and enzyme-inhibiting actions, Enfumox SM 500 ensures quicker infection clearance and minimizes relapse chances.
Dosage and Administration
- Recommended dose: One tablet twice daily or as prescribed by a healthcare professional.
- Should be taken after meals with a full glass of water to reduce gastrointestinal discomfort.
- Dosage may vary depending on the severity and type of infection, patient age, and renal function.
- Complete the full course as directed to avoid bacterial resistance or recurrence.
Possible Side Effects
Enfumox SM 500 is generally well tolerated, but some patients may experience mild and temporary side effects, including:
- Nausea, vomiting, or diarrhea
- Mild stomach upset or bloating
- Skin rash or itching (allergic reaction)
- Headache or dizziness
- Rarely, hypersensitivity reactions or transient liver enzyme elevation
If severe allergic reactions (e.g., swelling, breathing difficulty, or rash) occur, discontinue use and seek medical attention immediately.
Precautions
Use with caution in patients with a history of penicillin or cephalosporin allergy.
- Adjust dose in patients with renal or hepatic impairment.
- Not recommended for patients with infectious mononucleosis or severe gastrointestinal disorders.
- Prolonged use may lead to secondary infections such as fungal overgrowth.
- Should be used only under medical supervision during pregnancy or breastfeeding.
- Avoid alcohol consumption during the treatment course.
Storage Instructions
- Keep it in cool, dry place
- Keep away from direct sun light
- Keep away from the reach of children
