Description
Ceftriaxone and Sulbactam injection are marketed under the brand name Ctceff-SM-750 by Servocare Life Sciences. It is a potent antibiotic combination designed to treat severe bacterial infections. Ceftriaxone, a third-generation cephalosporin, provides broad-spectrum activity against Gram-positive and Gram-negative bacteria, while Sulbactam acts as a beta-lactamase inhibitor, protecting Ceftriaxone from degradation by resistant bacterial enzymes. This injectable formulation is commonly used for infections such as pneumonia, meningitis, sepsis, intra-abdominal infections, and complicated urinary tract infections.
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Advantages of Ceftriaxone and Sulbactam Injection
The medical advantages gained from Ceftriaxone and Sulbactam injection are given below:
- Provides broad-spectrum antibiotic coverage.
- Effective against beta-lactamase-producing bacteria.
- Combines bactericidal action with enzyme inhibition.
- Suitable for severe and resistant infections.
- Administered through IV or IM routes.
- Acts rapidly in critical conditions.
- Covers both gram-positive and gram-negative organisms.
- Useful for hospital-acquired infections.
- Allows for flexible dosing regimens.
- Helps reduce the development of antibiotic resistance.
- Effective for respiratory and CNS infections.
- Provides synergistic antibacterial activity.
- Suitable for post-surgical infections.
- Requires professional medical administration.
Dosage Instructions for Ceftriaxone and Sulbactam Injection
The dosage rules for Ceftriaxone and Sulbactam Injection are as follows:
- Administer intravenously or intramuscularly as directed.
- Typical adult dose is 1.5g to 3g daily.
- Divide the total daily dose into two administrations if needed.
- Reconstitute with sterile water before use.
- Administer IV infusion over 30-60 minutes.
- Rotate IM injection sites to prevent irritation.
- Adjust dosage for renal impairment if required.
- Do not mix with calcium-containing solutions.
- Complete the full prescribed course of treatment.
Storage Instructions for Ceftriaxone and Sulbactam Injection
The tips for storing Ceftriaxone and Sulbactam Injection are discussed here:
- Store unopened vials at controlled room temperature (20°C–25°C).
- Protect from light and moisture by keeping in the original packaging.
- Do not freeze the injection or the reconstituted solution.
- Discard unused reconstituted solution after the stability period expires.
- Keep vials away from direct sunlight and heat sources.
- Ensure the storage area is out of reach of children and pets.
- Do not use if the solution appears discolored or contains particles.
- Check the expiration date before use and never administer expired medication.
- Follow hospital or clinic protocols for storage if used in a healthcare facility.
Precautions of Ceftriaxone and Sulbactam Injection
The precautions of Ceftriaxone and Sulbactam Injection are mentioned below:
- Drink plenty of fluids and consume food before taking this medicine to avoid stomach upset.
- Never stop taking this drug early, as it may make the infection come back and harder to treat. Finish the full course.
- If you are experiencing an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking it, then immediately stop taking it and talk to your doctor.
Side Effects of Ceftriaxone and Sulbactam Injection
The side effects of having Ceftraxone and Sulbactam injection are as follows:
- Increased white blood cell count
- Decreased white blood cell count
- Low blood platelets
- Rash
- Diarrhea
- increased liver enzymes
- Injection site reactions (pain, swelling, redness)
Frequently Asked Questions (FAQs)
Can Ceftriaxone and Sulbactam injection cause allergic reactions?
Yes. Inform your doctor if you have penicillin/cephalosporin allergies. Discontinue if rash, swelling, or breathing difficulty occurs.
Why is sulbactam combined with ceftriaxone?
Sulbactam inhibits beta-lactamase enzymes, protecting ceftriaxone from degradation in resistant bacteria.
What if I miss a scheduled dose?
Contact your healthcare provider immediately. Do not double the dose.
Can it be self-administered at home?
No. Requires professional administration due to IV/IM route and monitoring needs.
