Description
Piperacillin Sodium (Sterile) I.P. 4000 mg and Tazobactam Sodium (Sterile) I.P. 500 mg – It is a broad-spectrum antibiotic dry injection widely used for treating serious bacterial infections. The tablet consists of two formulations, Piperacillin Sodium and Tazobactam Sodium. It offers potent and effective solutions to fight bacterial infection.
Piperacillin is a potent penicillin-class antibiotic that works against a wide range of gram-positive and gram-negative bacteria, while Tazobactam acts as a beta-lactamase inhibitor, protecting Piperacillin from bacterial resistance.
This combination is especially effective in hospitals for managing moderate to severe infections. The sterile dry powder formulation ensures stability, accurate dosing, and rapid action when administered intravenously under medical supervision. The dry injections are manufactured and sold by Servocare Life Sciences under the brand name PT Nac 4.5.
Working Mechanism of Piperacillin–Tazobactam Dry Injection
The Working Mechanism of Piperacillin Sodium and Tazobactam Sodium Dry Injection is mentioned as follows:
Piperacillin: Piperacillin works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins, weakening the cell wall and causing bacterial cell lysis and death, making it effective against a wide range of gram-positive and gram-negative bacteria.
Tazobactam Sodium: Tazobactam acts as a beta-lactamase inhibitor. It blocks enzymes produced by resistant bacteria that destroy antibiotics, thereby protecting Piperacillin and enhancing its antibacterial effectiveness
Benefits and Uses of Piperacillin Sodium and Tazobactam Sodium Dry Injection
The benefits of using Piperacillin Sodium I.P. 4000 mg and Tazobactam Sodium I.P. 500 mg are discussed as follows:
- Treats severe respiratory tract infections.
- Effective against urinary tract, skin, and soft tissue infections.
- Used in intra-abdominal and gynecological infections.
- Helpful in septicemia and hospital-acquired infections.
Side Effects of Piperacillin Sodium and Tazobactam Sodium Dry Injection
This combination medication may result in possible side effects, which go away as the body adjusts to the dosage. Consult your doctor if they persist or if you’re worried about them.
A list of them has been mentioned as follows
- Nausea or vomiting
- Diarrhea
- Injection site reactions
- Skin rash or itching
- Rarely, allergic reactions
Safety Measures and Precautions While Using Piperacillin Sodium and Tazobactam Sodium Dry Injection
Disclose your previous or recent health issues to your healthcare provider. A list of precautions and safety measures has been mentioned as follows:
- Use this medication only under medical supervision.
- Inform your doctor about penicillin allergies.
- Caution in patients with kidney or liver disorders.
- Not recommended during pregnancy unless prescribed.
- Consult your healthcare professional if you are breastfeeding before using this medication.
Storage Instructions
Follow the instructions mentioned as follows:
- Store in a cool, dry place below 25°C.
- Protect from light and moisture.
- Keep out of reach of children and pets.
- Store it in its own original packet.
Frequently Asked Questions (FAQs)
Q1. Is this injection effective against viral infections?
No, it works only against bacterial infections, not viruses like the flu or a common cold.
Q2. How is this dry injection administered?
It is reconstituted and given intravenously by a qualified healthcare professional.
Q3. Can this injection be used in severe infections?
Yes, it is commonly prescribed in hospitals for moderate to severe and life-threatening infections.
Q4. Are there any common side effects?
Possible side effects include nausea, diarrhea, skin rash, and mild injection site reactions.
Q5. Is it safe for patients allergic to penicillin?
No, patients with penicillin allergy should avoid this medication unless advised otherwise by a doctor.
Q6. Can it be used during pregnancy?
It should be used during pregnancy only if clearly prescribed by a healthcare professional.
Q7. Is the dosage the same for all patients?
No, dosage depends on infection severity, patient condition, and medical history.
Q8. Can kidney patients take this injection?
Dose adjustment may be required in patients with kidney impairment.
