Pregabalin IP 75mg and Methylcobalamin IP 750 mcg Tablets

Pregabalin+Methylcobalamin is a combination medicine used in the treatment of neuropathic pain. Neuropathic pain is a chronic health disorder in which nerve damage is caused due to progressive nerve disease or the nervous system’s malfunctioning. Neuropathic pain is observed in people who have suffered a trauma or nerve injury, diabetes, vitamin deficiencies, cancer, multiple sclerosis (disease of the brain and spinal cord), shingles (a viral infection), and HIV. Methylcobalamin is a type of vitamin B that helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha-2 delta ligand that decreases pain by modulating the calcium channel activity of the nerve cells. This sums up the combined action of Pregabalin+  Methylcobalamin in providing relief from neuropathic pain.

Do not self-medicate the medicine. Take the medicine as per the prescribed dosage and duration by the doctor. Do not crush, chew, or break the tablet. Swallow it whole with water. Some people may observe side effects such as dizziness, drowsiness, headache, anorexia (loss of appetite), nausea or vomiting, diarrhea, headache, hot sensation (burning pain), vision problems, and diaphoresis (sweating). Consult your doctor if the side effects persist or get severe. Store the tablets in a cool and dry place away from direct sunlight. Inform your doctor if you are allergic to Pregabalin+  Methylcobalamin or similar medicines. Also, share your complete medical history and current health conditions if any.

Uses of Pregabalin+Methylcobalamin Tablets 

Pregabalin+Methylcobalamin tablets are composed of two main ingredients Pregabalin and Methylcobalamin. Pregabalin works by decreasing the pain signals sent by a damaged nerve in the body. Whereas, Methylcobalamin helps rejuvenate and protect damaged nerve cells by producing a substance called myelin (outer protective layer of nerve cell – neuron). When taken regularly or as per the dosage prescribed by the doctor, combination medicine is used in the treatment of Neuropathic Pain. 

Side Effects of Pregabalin+Methylcobalamin Tablets 

The Pregabalin+Methylcobalamin tablets are potent medicine that can elicit mild to moderate side effects. Usually, the side effects are temporary and get resolved over time. However, if the side effects persist or get severe, immediately seek medical consultation. The list of side effects observed with the usage of Pregabalin+Methylcobalamin is given below:

• Dizziness, Sleepiness
• Headache
• Nasopharyngitis (inflammation of the throat and nasal passages)
• Increased appetite
• Confusion, Disorientation
• Abnormality of voluntary movements
• Balance disorder (loss of balance)
• Lethargy
• Blurred vision
• Vertigo
• Vomiting
• Constipation
• Muscle cramp
• Edema (swelling)
• Erectile dysfunction
• Weight gain

Drug Interactions 

Some drugs may interact with each other and cause negative health effects or lower efficacy.  Similar interactions can be seen in certain food items or under the influence of some health conditions.

Interaction with Drugs: 

• pain killer (oxycodone)
• opioids, antianxiety drugs (lorazepam)
• antacids (omeprazole)
• antibiotics (neomycin)
• anti-gout medication (colchicine)

Interaction with Diseases: 

• liver diseases
• kidney diseases
• heart problems
• alcoholism
• drug abuse
• suicidal tendencies

Precautions and Warnings 

1. Do not consume when taking this medicine as it can worsen the condition by increasing the side effects.

2. Pregabalin+Methylcobalamin is a category C  medicine that is not safe to use during pregnancy unless the doctor recommends taking the medicine.

3. The medicine is not safe for lactating mothers unless the doctor advises that the benefits outweigh the risk.

4. Do not drive or perform any activity requiring you to mentally concentrate as the medicine causes dizziness and hampers mental alertness.

5. Keep the medicine out of reach of children or pets. Properly dispose of expired and discarded medicines.

Frequently Asked Questions (FAQs) 

1. Can I stop taking Methylcobalamin+Pregabalin tablets when my pain is relieved?

No, you should not stop taking Methylcobalamin+Pregabalin even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Methylcobalamin+Pregabalin, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain, and sweating.

2. How long will the Methylcobalamin+Pregabalin take to show effects?

An initial benefit with Methylcobalamin+Pregabalin may be seen after 2 weeks of treatment. However, it may take around 2-3 months or more (in some patients) to see the full benefits.